Immunopathology during African Trypanosomosis
نویسندگان
چکیده
منابع مشابه
Alternative versus classical macrophage activation during experimental African trypanosomosis.
African trypanosomes are extracellular parasites causing sleeping sickness to human or nagana to livestock in sub-Saharan Africa. To gain insight into factors governing resistance/susceptibility to these parasites, the immune responses in mice infected with a Trypanosoma brucei phospholipase C null mutant (PLC(-/-)) or its wild type counterpart (WT) were compared. We found that the T. b. brucei...
متن کاملPan-African Tsetse and Trypanosomosis Eradication
20 In view of gathering baseline information about the prevalence of animal trypanosomosis, 21 the Pan African Tsetse and Trypanosomiasis Eradication Campaign (PATTEC) funded a cross 22 sectional survey in the Region of the Boucle du Mouhoun which constitutes the Northern 23 limit of the tsetse distribution in Burkina. This cross sectional study was carried out in 53 24 villages located in the ...
متن کامل[Immunology and immunopathology of African trypanosomiasis].
Human African trypanosomiasis (HAT) is characterized by a major deregulation of the immune system. Hypergammaglobulinemia, auto-antibodies, and immunodepression are cardinal features. Parasitemia occurs in waves due to the successive appearance of parasites with different variable glycoprotein surface antigens (VGSA). Antigenic variation enables parasites to elude the host's immune defenses. Al...
متن کاملDrugs and Drug Resistance in African Animal Trypanosomosis: A Review
Trypanosomosis is the most serious animal health problem in sub-Saharan Africa and prevents the keeping of animals over millions square kilometres of potentially productive land. Trypanocidal drugs belonging to different chemical families and they are used quite intensively in veterinary medicine. Drug for control of animal trypanosomosis relies essentially on three drugs namely homidium salts,...
متن کاملA Spatio-temporal Model of African Animal Trypanosomosis Risk
BACKGROUND African animal trypanosomosis (AAT) is a major constraint to sustainable development of cattle farming in sub-Saharan Africa. The habitat of the tsetse fly vector is increasingly fragmented owing to demographic pressure and shifts in climate, which leads to heterogeneous risk of cyclical transmission both in space and time. In Burkina Faso and Ghana, the most important vectors are ri...
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ژورنال
عنوان ژورنال: Journal of Tropical Diseases
سال: 2016
ISSN: 2329-891X
DOI: 10.4172/2329-891x.1000197